Goodhealth-108

Stomach cancer is common throughout the world and affects all races, it is more common in men than women, and has its peak age range between 40 and 60 years old. Stomach cancer mortality is higher in Japan and Chile, presumably because of the different diets in those countries where they are less dependent on red meat.
Over the last 25 years the incidence of stomach cancer in the western world has decreased by 50% and the resulting death rate is less than a third of what it used to be but in less developed countries it is still a major cause of death, probably because in these countries by the time the disease is diagnosed (usually by means of a Barium meal) the stomach cancer is at a very advanced stage.
TYPES OF STOMACH CANCER
There are several different types of stomach cancer, some of which are very rare. The most common types of stomach cancer start in the glandular cells of the stomach lining (adenocarcinomas), this is where stomach acid and digestive enzymes are made, and where most stomach cancers start. When the stomach cancer becomes more advanced, it can travel through the bloodstream and spread to organs such as the liver, lungs, and bones. Stomach cancers that start in the lymphatic tissue (lymphoma), in the stomach muscular tissue (sarcoma) or in the tissues that support the organs of the digestive system (gastrointestinal stromal tumors) are less common and are treated in different ways.
SIGNS AND SYMPTOMS
Early clues to stomach cancer are chronic dyspepsia and epigastric discomfort, followed in later stages by weight loss, anorexia, a feeling of fullness after eating, anemia and fatigue. Blood in the stools may also be present and if the Cancer is in the Cardia (top) vomiting may occur.
CAUSATION
The exact cause of stomach cancer is unknown although the presence of the Helicopter pylori bacterium seems to be a major factor. Predisposing factors include environmental influences such as smoking and high alcohol intake. Because stomach cancer is more common amongst those with a family history and with people with type A blood, genetic factors are also implicated. Dietary factors, particularly methods of food preservation such as pickling, smoking or salting also have an influence on the prevalence of stomach cancer.
DIAGNOSIS
Stomach cancer is diagnosed through an examination that may include an upper gastrointestinal (GI) series; endoscopy or gastroscopy where a thin flexible tube is passed down the throat so the doctor can see into the stomach, esophagus and upper part of the bowel Barium meals and Barium swallows. Because stomach cancer can spread to the liver, the pancreas, and other organs near the stomach as well as to the lungs, the doctor may order a CT scan, a PET scan, an endoscopic ultrasound exam, or other tests to check these areas.
Stomach cancer can spread (metastasize) to the esophagus or the small intestine, and can extend through the stomach wall to nearby lymph nodes and organs. Metastasis occurs in 80-90% of individuals with stomach cancer, with a five year survival rate of 75% in those diagnosed in early stages and less than 30% of those diagnosed in late stages.
TREATMENT
Although stomach cancer may be treated with surgery, radiation therapy, or chemotherapy, in many cases surgery is the treatment of choice. Even in patients whose disease is not considered surgically curable, resection offers a palliative effect and improves potential benefits from chemotherapy.
The nature and extent of the cancer determines what kind of surgery is most appropriate. Common surgical procedures include, partial and total removal of the stomach.
Antiemetics can control nausea, which increases as the cancer advances. In the more advanced stages, sedatives and tranquilizers may be necessary to control anxiety. Narcotics are commonly necessary to control sever and unremitting pain.
In some cases of advanced stomach cancer, a laser beam directed through an endoscope can vaporize most of the tumor and relieve obstruction without an operation.
PROGNOSIS
Stomach cancer is curable if detected early, but most people do not seek medical help until the disease is quite advanced, possibly because symptoms occur late and are often vague and non-specific. Eating fresh fruits and vegetables that contain antioxidant vitamins (such as A and C) appears to lower the risk of stomach cancer. The rate of stomach cancer is about doubled in smokers so the cessation of smoking is essential.
In the United States and most of the Western world, the 5-year survival rate ranges from 5% to 15%. In Japan, where stomach cancer often is diagnosed early, the 5 year survival rate is about 50%. Five year survival rates for more advanced stomach cancers range from, around 20% for those with regional disease to almost nil for those with distant metastases.
Treatment for metastatic stomach cancer can relieve symptoms and sometimes prolong survival, but long remissions are not common. The survival of inoperable stomach cancer is usually only a few months if untreated. With chemotherapy the average survival is about 12 months. If cancer is found before it has spread, the five-year relative survival rate is about 61%.

Lung cancer may be the most tragic cancer because in most cases, it might have been prevented, 87% of lung cancer cases are caused by smoking. Lung cancer has long been the most common cause of cancer death in men and since 1987 it has also become the most common cause of cancer death in women. Lung cancer is the second most commonly occurring form of cancer in most western countries and although the lung cancer incidence is less common in developing countries, the rapid increase in the popularity of smoking will see the number of lung cancer sufferers in those countries quickly catch up with the western world.
Lung cancers can arise in any part of the lung, and 90%-95% of cancers of the lung are thought to arise from the epithelial, or lining cells of the larger and smaller airways (bronchi and bronchioles); for this reason, lung cancers are sometimes called bronchogenic carcinomas or bronchogenic cancers.
The most common type of lung cancers are epidermoid carcinoma, small cell carcinoma, adenocarcinoma and large cell carcinoma.
Most experts agree that lung cancer is attributable to inhalation of carcinogenic pollutants by a susceptible host. Who is most susceptible? Any smoker over the age of 40, especially if they began smoking before the age of 15, have smoked 20 or more for 20 years, or worked with or near asbestos. Two other factors also increase susceptibility: exposure to carcinogenic industrial and air pollutants (asbestos, uranium, arsenic, nickel, iron oxides, chromium, radio active dust, and coal dust. ) and familial susceptibility.
SIGNS AND SYMPTOMS
Because early lung cancer usually produces no symptoms, the disease is often in an advanced stage when first diagnosed. Late stage signs are: with epidermoid and small cell carcinoma; smokers cough, hoarseness, wheezing, dyspnea, hemoptysis and chest pain. With adenocarcinoma and large cell carcinoma; fever, weakness, weight loss, anorexia and shoulder pain. In addition, hormone production which regulates various body functions may also be affected.
DIAGNOSIS
Firm diagnosis requires chest x rays, sputum cytology, CT scanning, bronchoscopy the examination of pleural fluid and biopsies. Other tests to detect metastasis include bone scans, bone marrow biopsy and CT scans of the brain and abdomen.
METASTASES
Lung cancer most often spreads to the liver, the adrenal glands, the bones, and the brain. Lung cancer that has metastasized to the bone causes bone pain, usually in the backbone (vertebrae), the thighbones, and the ribs. Lung cancer that spreads to the brain can cause difficulties with vision and weakness on one side of the body.
Lung cancer may grow into certain nerves in the neck, causing a droopy eyelid, small pupil, sunken eye, and reduced perspiration on one side of the face; together these symptoms are called Horner’s syndrome (see Autonomic Nervous System Disorders: Horner’s Syndrome). Lung cancer may grow directly into the esophagus, or it may grow near it and put pressure on it, leading to difficulty in swallowing. Lung cancer may also spread through the bloodstream to the liver, brain, adrenal glands, spinal cord, and bone.
TREATMENT
Treatment for lung cancer depends on the cancer’s specific cell type, how far it has spread, and the patient’s performance status. If investigations confirm lung cancer, CT scan and often positron emission tomography (PET) are used to determine whether the disease is localised and amenable to surgery or whether it has spread to the point where it cannot be cured surgically. Treatment is usually a combination of surgery, chemotherapy and radiation therapy.
Surgery is usually the first option. Chemotherapy can be used as a first line treatment for lung cancer or as additional treatment after surgery. Radiation therapy can be directed at your lung cancer from outside your body (external beam radiation) or it can be put inside needles, seeds or catheters and placed inside your body near the cancer (brachytherapy). Radiation therapy can be used alone or along with other lung cancer treatments. Radiation therapy can also be used to lessen side effects of lung cancer.
Treatment may not be as effective for patients with bone or liver metastases from lung cancer, excessive weight loss, ongoing cigarette use, or pre-existing medical conditions such as heart disease or emphysema. At some point, if you and your oncologist or primary care physician agree that treatment no longer is advisable, hospice care can provide comfort.

Colon cancer is cancer of the large intestine (colon), the lower part of your digestive system. Colon cancer is the second most common cancer in the USA with equal distribution between men and women. Colon cancer usually affects people over the age of 40, with the majority of people who are diagnosed with the condition being over 60 years of age. Colon cancer may affect any racial or ethnic group; however, some studies suggest that Americans of northern European heritage have a higher-than-average risk of colon cancer.
INCIDENCE
Colon cancer is more common in industrialized nations and in those societies where red meat is a major part of the diet, although evidence tends to suggest that merely changing your diet to white meat and seafood as in for instance Japan, tends to just swap stomach cancer for colon cancer. In almost all cases colon cancer is a treatable disease if caught early.
SIGNS AND SYMPTOMS
Colon cancer usually begins with the growth of benign growths such as polyps. Often there are no early symptoms. If signs and symptoms of colon cancer do appear, they may include: a change in your bowel habits, including diarrhea or constipation or a change in the consistency of your stool for more than a couple of weeks, rectal bleeding or blood in your stool, persistent abdominal discomfort, such as cramps, gas or pain, abdominal pain with a bowel movement, a feeling that your bowel doesn’t empty completely, weakness or fatigue and unexplained weight loss.
CAUSES
Colon cancer’s exact cause is unknown, but it appears to be influenced by both inherited and environmental factors. Studies show a concentration in areas of higher economic development suggesting a relationship to diet, particularly excess animal fat and low fiber. Other factors that increase the risk of developing colon cancer are: age over 40, the presence of other diseases of the digestive tract, family history and ulcerative colitis.
Development of colon cancer at an early age, or at multiple sites, or recurrent colon cancer, suggests a genetically transmitted form of the disease as opposed to the sporadic form. There also is a slight increased risk for colon cancer in the individual who smokes.
The most common colon cancer cell type is adenocarcinoma which accounts for 95% of cases.
DIAGNOSIS
The development of polyps of the colon usually precedes the development of colon cancer by five or more years. The American Gastroenterologial Association revised its screening guidelines in 2003 to recommend that people with two or more first-degree relatives with colorectal cancer or a first-degree relative with colon or rectal cancer before age 60 should have a screening colonoscopy beginning at age 40 or beginning 10 years prior to the age of the earlier colon cancer diagnosis in their family (whichever is earliest). Those with a first-degree relative diagnosed with colon cancer after age 60 or two second-degree relative with colon or rectal cancer should begin screening at age 40 with one of the methods listed above, such as annual sigmoidoscopy. The most common colon cancer screening tests are colonoscopy, sigmoidoscopy, and fecal occult blood test.
CT scans and Barium enemas are also routinely used for diagnosis of colon and rectal cancers.
TREATMENT
Almost all colon cancers are treated with surgery first, regardless of stage. The malignant tumor, adjacent tissues and any lymph nodes that may contain cancer cells are removed.
In colon cancer, chemotherapy after surgery is usually only given if the cancer has spread to the lymph nodes (Stage III). Radiation therapy may also be used to induce tumor regression. As with other cancer treatments, the incidence of side effects varies with patient health and the exact nature of the treatment.
PREVENTION
There is not an absolute method for preventing colon cancer. Still, there are steps an individual can take to dramatically lessen the risk or to identify the precursors of colon cancer so that it does not manifest itself. People who turn age 50, and all of those with a history of colon cancer in their families, should speak with their physicians about the most recent screening recommendations from physician and cancer organizations. They should watch for symptoms and attend all recommended screenings to increase the likelihood of catching colon cancer early. Exercise is believed to reduce the risk of colon cancer. Apparently, no association exists between frequency of bowel movement or laxative use and risk of colon cancer.
PROGNOSIS
Prognosis depends on the stage of the disease and the overall health of the patient. If diagnosed early, before the tumor has spread from the bowel, these treatments are very effective, with about 90% of patients alive five years after diagnosis. If the colon cancer does not come back (recur) within 5 years, it is considered cured. Prognosis is poor in patients with liver and lung metastases.

INTRODUCTION Lung cancer may also be the most tragic cancer because in most cases, it might have been prevented, 87% of lung cancer cases are caused by smoking. Lung cancer has long been the most common cause of cancer death in men and since 1987 it has also become the most common cause of cancer death in women. Lung cancer is the second most commonly occurring form of cancer in most western countries and although the lung cancer incidence is less common in developing countries, the rapid increase in the popularity of smoking will see the number of lung cancer sufferers in those countries quickly catch up with the western world. Lung cancers can arise in any part of the lung, and 90%-95% of cancers of the lung are thought to arise from the epithelial, or lining cells of the larger and smaller airways (bronchi and bronchioles); for this reason, lung cancers are sometimes called bronchogenic carcinomas or bronchogenic cancers. The most common type of lung cancers are epidermoid carcinoma, small cell carcinoma, adenocarcinoma and large cell carcinoma. Most experts agree that lung cancer is attributable to inhalation of carcinogenic pollutants by a susceptible host. Who is most susceptible? Any smoker over the age of 40, especially if they began smoking before the age of 15, have smoked 20 or more for 20 years, or worked with or near asbestos. Two other factors also increase susceptibility: exposure to carcinogenic industrial and air pollutants (asbestos, uranium, arsenic, nickel, iron oxides, chromium, radio active dust, and coal dust. ) and familial susceptibility. SIGNS AND SYMPTOMS Because early lung cancer usually produces no symptoms, the disease is often in an advanced stage when first diagnosed. Late stage signs are: with epidermoid and small cell carcinoma; smokers cough, hoarseness, wheezing, dyspnea, hemoptysis and chest pain. With adenocarcinoma and large cell carcinoma; fever, weakness, weight loss, anorexia and shoulder pain. In addition, hormone production which regulates various body functions may also be affected. DIAGNOSIS Firm diagnosis requires chest x rays, sputum cytology, CT scanning, bronchoscopy the examination of pleural fluid and biopsies. Other tests to detect metastasis include bone scans, bone marrow biopsy and CT scans of the brain and abdomen. METASTASES Lung cancer most often spreads to the liver, the adrenal glands, the bones, and the brain. Lung cancer that has metastasized to the bone causes bone pain, usually in the backbone (vertebrae), the thighbones, and the ribs. Lung cancer that spreads to the brain can cause difficulties with vision and weakness on one side of the body. Lung cancer may grow into certain nerves in the neck, causing a droopy eyelid, small pupil, sunken eye, and reduced perspiration on one side of the face; together these symptoms are called Horner’s syndrome (see Autonomic Nervous System Disorders: Horner’s Syndrome). Lung cancer may grow directly into the esophagus, or it may grow near it and put pressure on it, leading to difficulty in swallowing. Lung cancer may also spread through the bloodstream to the liver, brain, adrenal glands, spinal cord, and bone. TREATMENT Treatment for lung cancer depends on the cancer’s specific cell type, how far it has spread, and the patient’s performance status. If investigations confirm lung cancer, CT scan and often positron emission tomography (PET) are used to determine whether the disease is localised and amenable to surgery or whether it has spread to the point where it cannot be cured surgically. Treatment is usually a combination of surgery, chemotherapy and radiation therapy. Surgery is usually the first option. Chemotherapy can be used as a first line treatment for lung cancer or as additional treatment after surgery. Radiation therapy can be directed at your lung cancer from outside your body (external beam radiation) or it can be put inside needles, seeds or catheters and placed inside your body near the cancer (brachytherapy). Radiation therapy can be used alone or along with other lung cancer treatments. Radiation therapy can also be used to lessen side effects of lung cancer. Treatment may not be as effective for patients with bone or liver metastases from lung cancer, excessive weight loss, ongoing cigarette use, or pre-existing medical conditions such as heart disease or emphysema. At some point, if you and your oncologist or primary care physician agree that treatment no longer is advisable, hospice care can provide comfort.

Bone cancer is rare and accounts for less than 1% of all new tumors. Not all bone tumors are fatal in fact benign (non cancerous) abnormalities are more common than malignant ones. Most bone cancers are secondary and have been spread from another site. Primary bone cancer which starts in the bone is quite rare constituting less than one per cent of all malignant tumors. They are more common in males, especially in children and adolescents. The most common type of primary bone cancer is osteosarcoma. This type of carcinoma usually affects young adults. It can affect any bone, but the arms, legs and pelvis are more commonly affected. Other less common forms of primary bone cancer include Ewing sarcoma, malignant fibrous histiocytoma and chondrosarcoma.
Primary Bone Cancer
The causes of primary bone tumours are not known; however, adults who have Pagets disease (a bone disease) may have an increased risk.
Secondary bone cancer
Secondary bone cancer is the most common bone cancer. It is a carcinoma that starts somewhere else in the body and spreads (metastasises) to the bone. The most common cancers that spread to the bone originate in the breast, prostate, lung, kidney and thyroid.
Reticulum cell sarcoma of the bone
A cancerous tumor of the bone marrow presenting in more males than females.
Leukaemia
Cancer of the blood, which starts in the bone marrow
Symptoms of bore cancer
Symptoms tend to develop slowly and depend on the type, location, and size of the tumor. The signs and symptoms of bone cancer include: painful bones and joints, swelling of bones and joints, problems with movement, susceptibility to fractures. Less common symptoms include: unexplained weight loss, tiredness, fever and sweating.
Remember bone cancer is very rare so if you have any of these symptoms it is likely to be caused by another condition. Always see your doctor if you have for a diagnosis.
Causes
Although bone cancer does not have a clearly defined cause, researchers have identified several factors that increase the likelihood of developing these tumors. A small number of bone cancers are due to heredity.
Diagnosis
Bone cancer can present itself in any of the bones of the body, but it is diagnosed most often in the long bones of the arms and legs.
Diagnosing bone cancer involves a number of tests, including: X-rays and bone scans to show the exact location and size of the cancer (these are always done prior to biopsy), bone biopsy where a small sample of the cancer is removed from the bone and examined in the laboratory for the presence of malignant cells, Magnetic Resonance Imaging (MRI) scan similar to a CT scan but uses magnetism instead of x-rays to build three-dimensional pictures of your body.
Treatment
The treatment and prognosis of bone cancer depend upon multiple factors including the type and extent of the cancer, the patient’s age and overall health status. Tumors may be treated with surgery, radiation therapy, chemotherapy, or a combination of these.
Primary bone cancers:
The tumor, surrounding bone tissue and nearby lymph nodes are surgically removed. In severe cases, the affected limb may need to be amputated, but this is rare. Treatment may also include radiotherapy (x-rays to target and kill the cancer cells) and chemotherapy (anti-cancer drugs). These may be given before surgery, to shrink the cancer and/or afterwards to destroy any remaining cancer cells.
Secondary bone cancer:
Treatment depends on the treatment for the original tumor, but usually includes chemotherapy, radiotherapy or hormone therapy. Surgery may be needed to strengthen the affected bone.
Prognosis
Overall, the chance of recovery (prognosis) for bone cancers has improved significantly since the development of modern chemotherapy. The chance of recovery will depend on a variety of influences; if the cancer has spread, the type of bone cancer, the size of the tumour, location, the person’s general health and other individual factors.
If the tumor is very small and localized, the five-year survival rate is close to 90 percent. If the cancer has begun to spread, however, survival becomes more difficult. The five-year survival rate is only about 60 percent, and the prognosis is poor once the cancer spreads.
Bone cancer in cats and dogs
Bone carcinoma in dogs and cats can be a challenging disorder. Osteosarcoma is by far the most common bone tumour if dogs, usually striking the leg bones of larger breeds. Chemotherapy significantly prolongs the survival of animals with osteosarcoma when used in conjunction with surgery. For dogs Cisplatin alone or in combination with doxorubicin markedly improves survival time to a median of 8-10 months with the percentage of dogs alive after11 months at 50%.
Feline Osteosarcoma unlike its canine counterpart it has a much lower rate of metastasis and longer term survival can be expected with complete excision. Median survival for cats with osteosarcoma is approximately 2 years with many cats outreaching that.